Marc Boudreau
Marc Boudreau teaches courses in organic chemistry at both the undergraduate and graduate levels. Recent past research projects in our lab have focused on the synthesis of potential inhibitors of bacterial enzymes that confer antibiotic resistance, as well as the synthesis of unusual amino acids found in antimicrobial peptides. Not currently accepting new graduate students.
Courses Taught
- CHEM 546: Organic Chemistry Laboratory
- CHEM 548: Organic Chemistry II
- CHEM 651: Organic Chemistry I
- CHEM 652/652A: Organic Chemistry II
- CHEM 654: Organic Chemistry Laboratory
- CHEM 755/855: Advanced Organic Chemistry
- CHEM 777: Adv Syth and Char
- CHEM 795/911: Top/Synthetic Organic Chem
- INCO 790: Adv Rsrch Exp/Chemistry
Selected Publications
Lee, J., Boersma, A. J., Boudreau, M. A., Cheley, S., Daltrop, O., Li, J., . . . Bayley, H. (2016). Semisynthetic Nanoreactor for Reversible Single-Molecule Covalent Chemistry. ACS NANO, 10(9), 8843-8850. doi:10.1021/acsnano.6b04663
Leemans, E., Mahasenan, K. V., Kumarasiri, M., Spink, E., Ding, D., O'Daniel, P. I., . . . Mobashery, S. (2016). Three-dimensional QSAR analysis and design of new 1,2,4-oxadiazole antibacterials.. Bioorg Med Chem Lett, 26(3), 1011-1015. doi:10.1016/j.bmcl.2015.12.041
Ding, D., Boudreau, M. A., Leemans, E., Spink, E., Yamaguchi, T., Testero, S. A., . . . Mobashery, S. (2015). Exploration of the structure-activity relationship of 1,2,4-oxadiazole antibiotics.. Bioorg Med Chem Lett, 25(21), 4854-4857. doi:10.1016/j.bmcl.2015.06.044
Boudreau, M. A., Fishovitz, J., Llarrull, L. I., Xiao, Q., & Mobashery, S. (2015). Phosphorylation of BlaR1 in Manifestation of Antibiotic Resistance in Methicillin-Resistant Staphylococcus aureus and Its Abrogation by Small Molecules.. ACS Infect Dis, 1(10), 454-459. doi:10.1021/acsinfecdis.5b00086
Spink, E., Ding, D., Peng, Z., Boudreau, M. A., Leemans, E., Lastochkin, E., . . . Mobashery, S. (2015). Structure-activity relationship for the oxadiazole class of antibiotics.. J Med Chem, 58(3), 1380-1389. doi:10.1021/jm501661f
O'Daniel, P. I., Peng, Z., Pi, H., Testero, S. A., Ding, D., Spink, E., . . . Chang, M. (2014). Discovery of a new class of non-β-lactam inhibitors of penicillin-binding proteins with Gram-positive antibacterial activity.. J Am Chem Soc, 136(9), 3664-3672. doi:10.1021/ja500053x
Boudreau, M. A., Fisher, J. F., & Mobashery, S. (2012). Messenger functions of the bacterial cell wall-derived muropeptides.. Biochemistry, 51(14), 2974-2990. doi:10.1021/bi300174x
Liu, H., Boudreau, M. A., Zheng, J., Whittal, R. M., Austin, P., Roskelley, C. D., . . . Vederas, J. C. (2010). Chemical synthesis and biological activity of the neopetrosiamides and their analogues: revision of disulfide bond connectivity.. J Am Chem Soc, 132(5), 1486-1487. doi:10.1021/ja9102925
Wolfe, A. P., Tappert, R., Muehlenbachs, K., Boudreau, M., McKellar, R. C., Basinger, J. F., & Garrett, A. (2009). A new proposal concerning the botanical origin of Baltic amber.. Proc Biol Sci, 276(1672), 3403-3412. doi:10.1098/rspb.2009.0806
Spantulescu, M. D., Boudreau, M. A., & Vederas, J. C. (2009). Retention of configuration in photolytic decarboxylation of peresters to form chiral acetals and ethers.. Org Lett, 11(3), 645-648. doi:10.1021/ol802745n
Most Cited Publications