Department of Chemistry Research

Current Research Projects

Christopher Bauer designs psychometrically sound assessments to measure chemistry understanding, attitude, and motivation, and studies how that information may be used to develop improved inquiry-based curricula that enhances student learning and success, particularly at the college level. This work includes fundamental studies of student misconceptions of atoms, molecules, chemical reactions, and phenomena.


Student exam results chart

J. Res. Sci. Teach., 2015, 52(3), 319-346.


Erik Berda studies the design and synthesis of polymers programmed to adopt discrete tertiary structures, their self-assembly, responsive "smart" polymers, and other complex macromolecular architectures.


Polym. Chem., 2015, 6(2), 181-197.

Marc Boudreau utilizes organic chemistry and chemical biology to study antibiotic resistance in bacteria. New potential enzyme inhibitors or probes for target identification are synthesized in the laboratory. Their biological activity and mechanism of action is studied in detail, which is utilized to inform the rational design of improved inhibitors.

Christine Caputo designs and synthesizes new organic and organometallic complexes using Earth-abundant metals that can act as catalysts or precursors for the development of new photoactive materials. Current research projects employ photochemical and electrochemical techniques to study the catalytic conversion of small molecules into more valuable sustainable fuel precursors using sunlight.

Craig T. Chapman uses theory and computation to study the dynamical behavior of molecular systems, with special attention paid to the areas of energy, materials, and technology.  This includes simulating the photodynamics of excitonic and plasmonic systems with high level quantum computational techniques. 

Arthur Greenberg employs strained organic molecules to study biological and toxicological mechanisms. This includes chemical and enzymatic studies to investigate the reactions of cytochrome P450 isoforms with oxepins in order to understand metabolic ring-opening of benzene. Studies of twisted bridgehead bicyclic lactams are employed to model proteolysis, protein folding, and β-lactam antibiotics.

strained organic molecules

J. Org. Chem., 2014, 79(2), 517-528.

Margaret Greenslade applies physical chemistry techniques including spectroscopy and electron microscopy to study the optical, chemical and morphological properties of fine atmospheric particulates, known as aerosols. Aerosols play important roles in diverse fields such as climate change, air pollution, atmospheric chemistry, health and drug delivery.


J. Phys. Chem. A., 2012, 116(18), 4518-4527.

Richard Johnson uses a combination of high level theory and experiments to study reactive intermediates and complex organic reaction mechanisms. Current efforts are focused on proton and free radical catalyzed rearrangements of polycyclic aromatics. His group also develops new methods to predict the regio- and stereochemistry of organic reactions.

Anyin Li uses new materials and devices to improve analytical performance of mass spectrometry (MS). Current research projects aim at 1) enhancing sample-utilization efficiency in tandem MS characterization, and 2) developing novel quantitation method. Using MS based technologies, the group also creates atomically dispersed (noble metal) hybrid material for applications in catalysis, diagnosis, and flexible electronics. 

Gonghu Li is interested in bridging surface chemistry with molecular catalysis for solar energy applications. Particular projects include solar fuel generation by photochemical and photoelectrochemical CO2 reduction, TiO2 materials for energy and environmental photocatalysis.

Chem. Commun., 2014, 50(47), 6221-6224

Howard Mayne is interested in how the forces between molecules influence their behavior when in groups. He uses computations to model how these forces shape small clusters of molecules, and whether molecules can self assemble into patterns when placed on solid surfaces. The latter property is particularly important in materials science and nanotechnology.

molecule clusters

J. Phys. Chem. A., 2011, 115(25), 7044-7054.

Glen Miller performs research at the intersections of organic chemistry, materials science, and nanotechnology. His group synthesizes and characterizes both small molecules and derivatives of nanostructured carbons. They then utilize these species in structural materials and in thin-film electronic devices like photovoltaics and light emitting diodes.

crystal pattern structure

J. Phys. Chem. C., 2014, 118(46), 26955-26963.

Sam Pazicni divides his research interests between the classroom and the laboratory. In the classroom, his group explores how language relates to learning chemistry as well as abating students’ illusions of competence; in the laboratory, his group prepares and studies synthetic metalloenzymes and metalloproteins, based on collapsible polymer architectures.

comprehension and subscore chart

J. Chem. Educ., 2014, 91(12), 2045-2057.

Roy Planalp studies transition-metal coordination chemistry, which generally includes synthetic and physical inorganic chemistry applied to problems in the life sciences and environmental sciences.  The focus is on ligand design and synthesis, currently the development of ratiometric fluorescent sensors of copper for wastewater sampling, and mechanistic studies of phosphodiesterase metalloenzymes.

formation and determination chart

Dalton Trans. 2015, 44(26), 11887-11892.

W. Rudolf Seitz studies ratiometric fluorescent indicators for chemical sensing. One class of indicators senses bioavailable metal and can be incorporated into sensor arrays. Another consists of lightly cross-linked molecularly imprinted copolymers that bind polar organics and can be deposited on flat substrates.

negatively charged ligand figure

Sensors 2013, 13(1), 1341-1352.

Sterling Tomellini is interested in developing and applying analytical methodology, especially in the areas of chemical separations and spectroscopy for challenging analyses. He often collaborates with academic, government, and industrial researchers on multidisciplinary projects.

John Tsavalas specializes in the synthesis, characterization, and modeling of polymer colloids. His group is engaged in a wide range of activities including controlling colloidal morphology in polymeric nanoparticle synthesis; synthesizing stimuli-responsive coatings and composites; dynamic modeling of colloidal interactions and reaction kinetics, and probing the distribution of water within polymer colloids.

simulation of crossling reaction figure

Macromolecules, 2015, 48(1), 184-197.

Chuck Zercher develops synthetic methods and strategies designed to facilitate the preparation of novel biological mimics and natural products. The formation and selective fragmentation of cyclopropanes are key components of the selective methodologies. Synthetic targets include cyclopropanols designed as peptide mimics and cytotoxic spiroketal natural products.

molecular structure

J. Org. Chem., 2012, 77(20), 9171-9178.


Diverse Research Opportunities

The Department of Chemistry is the only department that has existed for the entire history of UNH; we have a long-standing tradition of achievement in the molecular sciences. Our vision for the future is not confined by the traditions of the past. We work to combine approaches and interface with other disciplines where interesting chemical questions exist. Our continuing commitment to quality and innovation is reflected in the multifaceted research themes of the Department:

analytical methods and methods development (AM&MD)

This research effort develops tools and methods to analyze, characterize, manipulate, and sense molecules, ions, and small particles, especially as related to toxins, environmental species, and materials.

bio-inspired chemistry and chemical biology (BIO)

In these areas, expertise from inorganic/organic synthesis, analytical chemistry, and biochemistry are applied to biological systems at the molecular and macromolecular levels as well as in whole cells.

chemistry education research (CER)

We are one of the few Chemistry Departments in which multiple faculty members perform Chemistry Education Research—combining disciplinary expertise with methodologies/models from education, the learning sciences, and psychology to better understand and improve chemistry teaching and learning.

energy and environmental science (EN&ENV)

These areas make use of synthetic, physical, and analytical chemistry to molecularly harness energy from sunlight and to probe/sense trace species in, and potential chemical threats to, the environment.

macromolecules, materials, and nanoscience (MM&N)

Materials-related research is very strong in our Department, and it encompasses a diverse range of projects, including molecular materials, nanomaterials, computational chemistry, surface chemistry, colloids, and polymers.

Our Faculty

The diverse research interests of our faculty do not permit their easy classification in to the traditional areas of Chemistry.  However, they are listed here in a matrix representing the spectrum of department research, with their traditional classification indicated by a diamond (♦) and interdisciplinary research interests indicated by a closed circle ().


Faculty Member
Christopher Bauer              
Erik Berda              
Marc Boudreau              
Christine Caputo              
Craig Chapman            
Arthur Greenberg              
Margaret Greenslade            
Richard Johnson              
Anyin Li          
Gonghu Li            
Howard Mayne              
Glen Miller            
Sam Pazicni            
Roy Planalp            
W. Rudolf Seitz          
John Tsavalas            
Sterling Tomellini            
Charles Zercher