Phone (603) 862- 3294
Materials found in nature have a variety of properties and functions that have yet to be recapitulated in modern synthetic materials. Using semisynthetic and biologically derived macromolecules we hope to create soft materials that capture the form and function of biological tissues. The natolab will tackle this goal in three main areas: Control of topological features in soft materials to control bulk mechanical properties, the creation and design of novel living supramolecular polymerization monomers, and far-from-equilibrium materials.
Twitter account: https://twitter.com/thenatolab
Courses Taught
- BIOL 799H: Honors Senior Thesis
- BMCB 501: Biological Chemistry
- BMCB 799H: Honors Senior Thesis
- BMS 795W: Investigations Biomedical Sci
- CHEM 550: Organic Chemistry Laboratory
- CHEM 740/840: Chemical Biology
- CHEM 741/895: Chemistry Biology Lab
- CHEM 795/895: Special Topics
- CHEM 795/918: SpecialTopics/Chemical Biology
- INCO 590: Student Research Experience
- INCO 790: Advanced Research Experience
Selected Publications
Pierini, N. G., Paiva, W. A., Durant, O. C., Dobbins, A. M., Wheeler, B. B., Currier, M. E., . . . Oldenhuis, N. J. (2025). Generation of topologically defined linear and cyclic DNA bottle brush polymers via a graft-to approach.. Polym Chem. doi:10.1039/d5py00082c
Hughes, S. M., Aykanat, A., Pierini, N. G., Paiva, W. A., Weeks, A. A., Edwards, A. S., . . . Oldenhuis, N. J. (2024). DNA‐Intercalating Supramolecular Hydrogels for Tunable Thermal and Viscoelastic Properties. Angewandte Chemie, 136(45). doi:10.1002/ange.202411115
Hughes, S. M., Aykanat, A., Pierini, N. G., Paiva, W. A., Weeks, A. A., Edwards, A. S., . . . Oldenhuis, N. J. (2024). DNA-Intercalating Supramolecular Hydrogels for Tunable Thermal and Viscoelastic Properties.. Angew Chem Int Ed Engl, 63(45), e202411115. doi:10.1002/anie.202411115
Paiva, W. A., Alakwe, S. D., Marfai, J., Jennison-Henderson, M. V., Achong, R. A., Duche, T., . . . Oldenhuis, N. J. (2024). From Bioreactor to Bulk Rheology: Achieving Scalable Production of Highly Concentrated Circular DNA.. Adv Mater, 36(35), e2405490. doi:10.1002/adma.202405490
Lundberg, D. J., Brown, C. M., Bobylev, E. O., Oldenhuis, N. J., Alfaraj, Y. S., Zhao, J., . . . Johnson, J. A. (2024). Nested non-covalent interactions expand the functions of supramolecular polymer networks.. Nat Commun, 15(1), 3951. doi:10.1038/s41467-024-47666-x
