harish_vashisth

Harish Vashisth

Professor
of Chemical Engineering & Bioengineering
Phone: (603) 862-2483
Office: Kingsbury Hall, Room S344b, Durham, NH 03824
Websites:

RESEARCH EXPERTISE: Computational Biophysics; Chemical Physics; Soft Matter and Self-assembly; Biomolecular Modeling and Simulations

 

HONORS AND AWARDS:
2025/ Impact Award, Computational Molecular Science and Engineering, American Institute of Chemical Engineers (AIChE)
2025/ NIH Outstanding Investigator (MIRA) Award
2024/ Outstanding Professor Excellence in Research Award, College of Engineering & Physical Sciences (CEPS), UNH
2023/ John T. and Doris H. Carpenter Professorship
2020/ NIH Outstanding Investigator (MIRA) Award
2016/  NSF CAREER Award

 

Courses Taught

  • CHBE 603: Applied Math for Chem Engineer
  • CHBE 695: Chemical Engineering Project
  • CHBE 755/855: Computational Molecular Bioeng
  • CHBE 840: Advanced Transport Phenomena
  • CHBE 923: Adv Chem Engg Thermodynamics
  • CHBE 999: Doctoral Research
  • CHE 900: Seminar
  • CHE 923: Adv Chem Eng Thermodynamics
  • CHE 999: Doctoral Research
  • INCO 790: Advanced Research Experience

Education

  • Ph.D., Chemical Engineering, Drexel University
  • B.Tech., Chemical Engineering, National Instit of Tech

Research Interests

  • 3D Modeling / Visualization
  • Bioengineering
  • Biological Modeling
  • Biological Polymers
  • Biomedical Engineering
  • Biomimetics
  • Biomolecular Science
  • Biopharmaceuticals
  • Biophysical Interactions
  • Biophysics
  • Chemical Engineering
  • Chemical Physics
  • Computer Modeling
  • Computer Simulation/Modeling

Selected Publications

  • Amissah, T. E., Levintov, L., & Vashisth, H. (2026). Nonadditive Conformational Effects of tRNA Core Modifications.. J Chem Inf Model, 66(20), 13519-13533. doi:10.1021/acs.jcim.6c02045

  • Levintov, L., Moaseri, E., Behbahani, N., Li, L., & Vashisth, H. (2026). Conformational Dynamics of Phase-Separating Methacrylated Carbohydrates.. JACS Au, 6(10), 5894-5905. doi:10.1021/jacsau.6c01217

  • Nguyen, S. V., & Vashisth, H. (2026). Field-driven peptide transport across the inner mitochondrial membrane via a transient membrane pore.. J Chem Phys, 165(9). doi:10.1063/5.0349142

  • Levintov, L., & Vashisth, H. (2026). Molecular Interactions of Viral Insulin/IGF-Like Peptides With Zebrafish Receptors.. Proteins. doi:10.1002/prot.70168

  • Levintov, L., Orellana, E. A., & Vashisth, H. (2026). Thermophysical Properties of a tRNA Isodecoder.. J Phys Chem B, 130(31), 7867-7875. doi:10.1021/acs.jpcb.6c03075

  • Shen, Y. -X., Song, W. C., Barden, D. R., Ren, T., Lang, C., Feroz, H., . . . Kumar, M. (2018). Achieving high permeability and enhanced selectivity for Angstrom-scale separations using artificial water channel membranes. NATURE COMMUNICATIONS, 9. doi:10.1038/s41467-018-04604-y

  • Dickson, A., Tiwary, P., & Vashisth, H. (2017). Kinetics of Ligand Binding Through Advanced Computational Approaches: A Review. CURRENT TOPICS IN MEDICINAL CHEMISTRY, 17(23), 2626-2641. doi:10.2174/1568026617666170414142908

  • Vashisth, H., Maragliano, L., & Abrams, C. F. (2012). "DFG-Flip" in the Insulin Receptor Kinase Is Facilitated by a Helical Intermediate State of the Activation Loop. BIOPHYSICAL JOURNAL, 102(8), 1979-1987. doi:10.1016/j.bpj.2012.03.031

  • Strunk, B. S., Loucks, C. R., Su, M., Vashisth, H., Cheng, S., Schilling, J., . . . Skiniotis, G. (2011). Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates. SCIENCE, 333(6048), 1449-1453. doi:10.1126/science.1208245

  • Vashisth, H., & Abrams, C. F. (2008). Ligand Escape Pathways and (Un)Binding Free Energy Calculations for the Hexameric Insulin-Phenol Complex. BIOPHYSICAL JOURNAL, 95(9), 4193-4204. doi:10.1529/biophysj.108.139675

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  • Most Cited Publications